Miss All Star United States Pageant Charities
Official National Pageant Charities
Charity in lieu of State Gifts The Miss All-Star United States Pageant asks that you make a donation to one of the official charities/scholarships instead of bringing and giving a state gift to the other contestants.
There is power in number and a little goes a long way. Checks will be presented to the National Pageant Charities at Nationals.
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MHE / MO / HME is a genetic bone disorder in which benign cartilage-capped bone tumors grow outward from the metaphyses oflong bones, growth plates or from the surface of flat bones throughout the body. The severity of this disease varies widely.Some patients may have as few as two tumors, but most patients develop many more and the numbers of tumors can run into the hundreds.
These cartilage-capped bone tumors are called Exostoses / Osteochondroma and may be sessile or pedunculated and vary
widely in size and shape. Pedunculated Exostoses / Osteochondroma is when a stalk is present, the structure is called
pedunculated. These have a Broccoli like appearance with stalk and growth towards the end of the stalk. Sessile Exostoses
/Osteochondroma have a broad-base attachment to the outer bone, called the “cortex”. These have a lumpy / bumpy appearance (When no stalk is present, these are called sessile)
These Exostoses / Osteochondromas can cause numerous problems, including: compression of peripheral nerves or blood
vessels; irritation of tendons and muscles resulting in pain and loss of motion; skeletal deformity; short stature; limb length discrepancy; chronic pain and fatigue; mobility issues; early onset arthritis; and an increased risk of developing malignant tumor transformation (chondro-sarcoma) reported risk of 2%-5% over life time. It is not uncommon for MHE / MO / HME patients to undergo numerous surgical procedures throughout their lives to remove painful or deforming Exostoses / Osteochondromas and or to correct limb length discrepancies and improve range of motion.
Surgery, physical therapy and pain management are currently the only options available to MHE / MO / HME patients, but their success varies from patient to patient and many struggle with chronic pain, fatigue and mobility problems throughout their lives.
MHE / MO / HME is a genetic autosomal dominant hereditary disorder. This means that a patient with MHE / MO / MHE has a 50% chance of transmitting this disorder to his / her children. Approximately 10% -20% of individuals with MHE / MO / HME have the condition as a result of a spontaneous mutation are thus the first person in their family to be affected.
There are two known genes found to cause MHE / MO / HME they are EXT1 located on chromosome 8q23-q24 and EXT2 located on chromosome 11p11-p12. Approximately 60 to 70 % of mutations are located in the EXT1 gene and 20 to 30% are located in the EXT2 gene. In 10 to 20% of the patients, no mutation is found.
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